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"A typical dose of caffeine (100 mg) can be consumed up to 4 hours prior to bedtime without significant effect on subsequent sleep. To mitigate caffeine-induced sleep disruptions, it is ...
In contrast to the sleeping agents, a go pill refers to a wakefulness-promoting agent used for fatigue management, especially in a military combat-readiness context; this is contrasted with a no-go pill, which is used to promote sleep in support of combat operations. A go pill generally contains one of the following drugs:
"If you sense that you may be a slow metabolizer of caffeine, it is best to limit caffeine to a maximum of 200 milligrams per day and stop all caffeine intake at least eight hours before bedtime ...
You won't even miss your morning cup of coffee.
Consuming caffeine to stay awake at night may lead to sleeplessness, anxiety, frequent nighttime awakenings, and overall poorer sleep quality. [139] The main metabolite of melatonin (6-sulfatoxymelatonin) gets reduced with consumption of caffeine in the day, which is one of the mechanisms by which sleep is interrupted. [137]
Doses as low as 100 mg/day, such as a 6 oz (170 g) cup of coffee or two to three 12 oz (340 g) servings of caffeinated soft-drink, may continue to cause sleep disruption, among other intolerances. Non-regular caffeine users have the least caffeine tolerance for sleep disruption. [79]
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