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Simvastatin is contraindicated with pregnancy, breastfeeding, and liver disease. [16] Pregnancy must be avoided while on simvastatin due to potentially severe birth defects. Patients cannot breastfeed while on simvastatin due to potentially disrupting the infant's lipid metabolism. [ 17 ]
Statin drugs include: Pravastatin. Simvastatin. Atorvastatin. Rosuvastatin. You may be prescribed a statin for a short period of time, or be prescribed a statin alongside other treatments or ...
Includes factors that can increase the risk of heart disease, such as kidney disease, obesity and a marker of poor blood sugar control (hemoglobin A1C). Calculates risk separately for men and women.
Regarding cardiovascular events, patients with chronic kidney disease saw a reduction in vascular and major atherosclerotic events when on simvastatin and ezetimibe compared to placebo. [25] This same combination was also shown to reduce death, major coronary events, and nonfatal stroke in patients after acute coronary syndromes.
There is some evidence that appropriate use of statin medications in people with chronic kidney disease who do not require dialysis may reduce mortality and the incidence of major cardiac events by up to 20% and are not that likely to increase the risk of stroke or kidney failure. [16] Asthma
New research from the University of Hong Kong found that statins effectively lowered the risk of cardiovascular and all-cause mortality among adults 60 years of age and older — including people ...
Diabetic nephropathy, also known as diabetic kidney disease, [5] is the chronic loss of kidney function occurring in those with diabetes mellitus. Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria ...
In fact, sticking close to the diet has recently been shown, in a large-scale, long-term (30-year) cohort study published last year in the journal Circulation, to lower heart disease risk by 14%.