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Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]
Cancer can be considered a very large and exceptionally heterogeneous family of malignant diseases, with squamous-cell carcinomas comprising one of the largest subsets. [19] [20] [21] All SCC lesions are thought to begin via the repeated, uncontrolled division of cancer stem cells of epithelial lineage or characteristics.
Acute lymphoblastic leukemia (ALL) 4.0% Acute myeloid leukemia (AML) 8.7% Chronic lymphocytic leukemia (CLL) sorted under lymphomas according to current WHO classification; called small lymphocytic lymphoma (SLL) when leukemic cells are absent. 10.2% Chronic myelogenous leukemia (CML) 3.7% Acute monocytic leukemia (AMoL) 0.7% Other leukemias 3.1%
CLL has also been reported to convert into other more aggressive diseases such as lymphoblastic lymphoma, hairy cell leukemia, high grade T cell lymphomas, [25] acute myeloid leukemia, [26] lung cancer, brain cancer, melanoma of the eye or skin, [27] [28] salivary gland tumors, and Kaposi's sarcomas. [29]
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).
Primary cutaneous diffuse large B-cell lymphoma, leg type is an aggressive B-cell lymphoma that is often resistant to therapy and carries a poor prognosis, [5] i.e., they have a 5-year disease-specific survival rate of 43% or 70% depending on whether their cancer cells have or do not have, respectively, inactivating mutations in both of their ...
Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions. [1] This condition may be contrasted with leukemids , which are skin lesions that occur with leukemia, but which are not related to leukemic cell infiltration.
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy with features of cutaneous lymphoma (e.g. malignant plasmacytoid dendritic cell infiltrations into the skin to form single or multiple lesions) and/or leukemia (i.e. malignant plasmacytoid dendritic cells in blood and bone marrow). [2]
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