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  2. Germ cell tumor - Wikipedia

    en.wikipedia.org/wiki/Germ_cell_tumor

    The 1997 International Germ Cell Consensus Classification [17] is a tool for estimating the risk of relapse after treatment of malignant germ-cell tumor. A small study of ovarian tumors in girls [18] reports a correlation between cystic and benign tumors, and conversely, solid and malignant tumors. Because the cystic extent of a tumor can be ...

  3. Mediastinal germ cell tumor - Wikipedia

    en.wikipedia.org/wiki/Mediastinal_germ_cell_tumor

    The treatment for mediastinal nonseminomatous germ cell tumors should follow guidelines for poor-prognosis testicular cancer. Initial treatment with four courses of bleomycin, etoposide, and cisplatin, followed by surgical resection of any residual disease, is considered standard therapy.

  4. Teratoma - Wikipedia

    en.wikipedia.org/wiki/Teratoma

    Teratomas belong to a class of tumors known as nonseminomatous germ cell tumor. All tumors of this class are the result of abnormal development of pluripotent cells: germ cells and embryonal cells. Teratomas of embryonic origin are congenital; teratomas of germ cell origin may or may not be congenital. The kind of pluripotent cell appears to be ...

  5. Embryonal carcinoma - Wikipedia

    en.wikipedia.org/wiki/Embryonal_carcinoma

    In the testis pure embryonal carcinoma is also uncommon, and accounts for approximately ten percent of testicular germ cell tumours. However, it is present as a component of almost ninety percent of mixed nonseminomatous germ cell tumours. The average age at diagnosis is 31 years, and typically presents as a testicular lump which may be painful.

  6. Germinoma - Wikipedia

    en.wikipedia.org/wiki/Germinoma

    Dysgerminoma is the most common type of malignant germ-cell ovarian cancer. Dysgerminoma usually occurs in adolescence and early adult life; about 5% occur in prepubertal children. Dysgerminoma is extremely rare after age 50. It occurs in both ovaries in 10% of patients and, in a further 10%, a microscopic tumor is in the other ovary. [citation ...

  7. Ovarian germ cell tumors - Wikipedia

    en.wikipedia.org/wiki/Ovarian_Germ_Cell_Tumors

    Ovarian germ cell tumors (OGCTs) are heterogeneous tumors that are derived from the primitive germ cells of the embryonic gonad, which accounts for about 2.6% of all ovarian malignancies. [1] There are four main types of OGCTs, namely dysgerminomas , yolk sac tumor , teratoma , and choriocarcinoma .

  8. Elevated alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Elevated_alpha-fetoprotein

    Rarely, high MSAFP is due to endodermal sinus tumor (EST) or another germ cell tumor containing EST. These tumors can occur in the pregnant woman (often as an ovarian tumor) or in the fetus. MSAFP below normal is associated with a smaller number of conditions, including Down syndrome and Trisomy 18. Diabetic patients also have lower levels.

  9. Germ cell neoplasia in situ - Wikipedia

    en.wikipedia.org/wiki/Germ_cell_neoplasia_in_situ

    Not all germ cell tumors (GCTs) arise from intratubular germ cell neoplasia. The following testicular GCTs do not arise from ITGCN: Spermatocytic tumor [5] Pediatric Yolk sac tumors (endodermal sinus tumour). [6] This is currently an area of controversy as some authors dispute the absence of ITGCN in these cases. [3] Teratoma (rare exceptions) [3]