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OTL-103 is an autologous cell therapy that uses the patient's own CD34+ cells collected from bone marrow or peripheral blood. These are then transfected with a lentiviral vector that encodes for a functional Wiskott–Aldrich syndrome protein. The transfected cells are then reinfused to the patient. [7]
Vectorcardiography (VCG) is a method of recording the magnitude and direction of the electrical forces that are generated by the heart by means of a continuous series of vectors that form curving lines around a central point.
This vector system has been promoted for treating cancer and indeed the first gene therapy product to be licensed to treat cancer, Gendicine, is an adenovirus. Gendicine, an adenoviral p53-based gene therapy was approved by the Chinese food and drug regulators in 2003 for treatment of head and neck cancer.
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Type 1 develops its characteristics from the horizontal vector, and Type 2 develops its characteristics from the vertical vector. Type 1 CH occurs much more common (15x) than Type 2 CH. Wolford et al. [10] in 2014, developed an updated classification of condylar hyperplasia. In 1986, Slootweg & Muller devised a histopathological classification ...
Delandistrogene moxeparvovec, sold under the brand name Elevidys, is a recombinant gene therapy used for the treatment of Duchenne muscular dystrophy. [3] It is designed to deliver into the body a gene that leads to production of Elevidys micro-dystrophin that contains selected domains of the dystrophin protein present in normal muscle cells. [3]
Despite being a Microsoft Research internal project, Skinput has been demonstrated publicly several times. The first public appearance was at Microsoft's TechFest 2010, where the recognition model was trained live on stage, during the presentation, followed by an interactive walkthrough of a simple mobile application with four modes: music player, email inbox, Tetris, and voice mail. [8]
A patient-reported outcome (PRO) is a health outcome directly reported by the patient who experienced it. It stands in contrast to an outcome reported by someone else, such as a physician -reported outcome, a nurse -reported outcome, and so on.