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If the buildup happens in the brain, then this may lead to a stroke. Some physical exams findings suggestive of hyperlipidemia are xanthomas, which are yellow "bumps" found on the skin, on the arms, legs, or trunk. Xanthelasmas are similar deposits of fat under the skin, but these appear on the eyelids. [7]
As mentioned above, abdominal fat is linked with cardiovascular disease, diabetes, and cancer. Specifically it is the deepest layer of belly fat (the fat that cannot be seen or grabbed) that poses health risks, as these "visceral" fat cells produce hormones that can affect health (e.g. increased insulin resistance and/or breast cancer risk).
Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease (NAFLD), [a] is a type of chronic liver disease.This condition is diagnosed when there is excessive fat build-up in the liver (hepatic steatosis), and at least one metabolic risk factor.
Both types of fat can contribute to belly fat. “Unhealthy fat can build up in many areas of the body, and all types of excess fat can lead to health problems,” Dr. Rairigh says.
[4] [12] Dual-energy X-ray Absorptiometry may be useful by providing both regional %fat measurements, and direct visualization of fat distribution by means of a "fat shadow". [13] A genetic confirmation is sometimes possible, depending on the subtype. However, in up to 40% of partial lipodystrophy patients, a causative gene has not been ...
When in need of glucose the body of a person with a fatty-acid metabolism disorder will still send fats to the liver. The fats are broken down to fatty acids. The fatty acids are then transported to the target cells but are unable to be broken down, resulting in a build-up of fatty acids in the liver and other internal organs.
Biomagnification is the buildup of concentration of a substance (x) in a food chain. For example the DDT concentration in parts per million increases with trophic level. Concentrations build up in organism's fat and tissue. Predators accumulate higher levels than prey.
Lipohypertrophy [1] is a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin. It may be unsightly, mildly painful, and may change the timing or completeness of insulin action. It is a common, minor, chronic complication of diabetes mellitus.