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The nitrates are used for the treatment and prevention of angina and acute myocardial infarction, while molsidomine acts too slowly to be useful for the treatment of acute angina. [2] For quick action in the treatment of angina, glyceryl trinitrate is used in form of a sublingual spray (nitro spray) or as soft capsules to be crunched.
Topical nifedipine has been shown to be as effective as topical nitrates for anal fissures. [18] Nifedipine is also used in high-altitude medicine to treat high altitude pulmonary edema. [19] Nifedipine is one of the main choices for the treatment of Prinzmetal angina due to its vasodilating effects on the coronary arteries. [2]
Short-acting nitrates can be taken upon the onset of symptoms and should provide relief within minutes. [6] Nitroglycerin is the most common short-acting nitrate and it is applied under the tongue. [6] Long acting nitrates are taken 2-3 times per day and can be used to prevent angina. [6]
Short-acting nitrates are used to abort angina attacks that have occurred, while longer-acting nitrates are used in the prophylactic management of the condition. Agents include glyceryl trinitrate (GTN) , pentaerythritol tetranitrate , isosorbide dinitrate and isosorbide mononitrate .
It can have many potential causes, including genetics, lifestyle habits, and underlying health issues. Some types of cardiovascular disease, such as some cardiomyopathies, develop due to factors ...
Isosorbide dinitrate is in the nitrate family of medications and works by dilating blood vessels. [1] Isosorbide dinitrate was first written about in 1939. [3] It is on the World Health Organization's List of Essential Medicines. [4] Isosorbide dinitrate is available as a generic medication. [1] [5] A long-acting form exists. [1]
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Angina, also known as angina pectoris, is chest pain or pressure, usually caused by insufficient blood flow to the heart muscle (myocardium). [2] It is most commonly a symptom of coronary artery disease. [2] Angina is typically the result of partial obstruction or spasm of the arteries that supply blood to the heart muscle. [3]