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The journal was established in 1970. Prior to that time, original research articles covering topics in infection and immunity were published in a section of the Journal of Bacteriology. As the size of this section grew, the need for a separate journal publishing peer-reviewed research in this area became apparent. [1]
The following outline is provided as an overview of and topical guide to concepts related to infectious diseases in humans.. Infection – transmission, entry/invasion after evading/overcoming defense, establishment, and replication of disease-causing microscopic organisms (pathogens) inside a host organism, and the reaction of host tissues to them and to the toxins they produce.
Cryptococcus neoformans is a fungus that causes cryptococcosis, which can lead to pulmonary infection as well as nervous system infections, like meningitis. [25] [26] Histoplasma capsulatum is a species of fungus known to cause histoplasmosis, which can present with an array of symptoms, but often involves respiratory infection. [27] [28]
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. [1] An infectious disease , also known as a transmissible disease or communicable disease , is an illness resulting from an infection.
Adaptive (or acquired) immunity creates an immunological memory leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination. Dysfunction of the immune system can cause autoimmune diseases, inflammatory diseases and cancer.
Premunition, also known as infection-immunity, [1] is a host response that protects against high numbers of parasite and illness without eliminating the infection. [2] This type of immunity is relatively rapid, progressively acquired, short-lived, and partially effective. [ 3 ]
An infected individual may develop a short-term immunity but that disappears after a few months, and immunity to one strain does not confer immunity to another. [86] An immunisation experiment was done in 1950 in which 16 volunteers still developed the infection after 11–25 months of primary infection. [ 88 ]
Pneumococcal infection is an infection caused by the bacterium Streptococcus pneumoniae. [ 1 ] S. pneumoniae is a common member of the bacterial flora colonizing the nose and throat of 5–10% of healthy adults and 20–40% of healthy children. [ 2 ]