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The journal was established in 1970. Prior to that time, original research articles covering topics in infection and immunity were published in a section of the Journal of Bacteriology. As the size of this section grew, the need for a separate journal publishing peer-reviewed research in this area became apparent. [1]
The following outline is provided as an overview of and topical guide to concepts related to infectious diseases in humans.. Infection – transmission, entry/invasion after evading/overcoming defense, establishment, and replication of disease-causing microscopic organisms (pathogens) inside a host organism, and the reaction of host tissues to them and to the toxins they produce.
Premunition, also known as infection-immunity, [1] is a host response that protects against high numbers of parasite and illness without eliminating the infection. [2] This type of immunity is relatively rapid, progressively acquired, short-lived, and partially effective. [ 3 ]
Cryptococcus neoformans is a fungus that causes cryptococcosis, which can lead to pulmonary infection as well as nervous system infections, like meningitis. [25] [26] Histoplasma capsulatum is a species of fungus known to cause histoplasmosis, which can present with an array of symptoms, but often involves respiratory infection. [27] [28]
Innate immune systems are found in all animals. [2] If pathogens successfully evade the innate response, vertebrates possess a second layer of protection, the adaptive immune system, which is activated by the innate response. [3] Here, the immune system adapts its response during an infection to improve its recognition of the pathogen.
An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. [1] An infectious disease, also known as a transmissible disease or communicable disease, is an illness resulting from an infection.
Correlates of immunity or correlates of protection to a virus or other infectious pathogen are measurable signs that a person (or other potential host) is immune, in the sense of being protected against becoming infected and/or developing disease. For many viruses, antibodies and especially neutralizing antibodies serve as
A representation of the cholera epidemic of the 19th century. For thousands of years mankind has been intrigued with the causes of disease and the concept of immunity. The prehistoric view was that disease was caused by supernatural forces, and that illness was a form of theurgic punishment for "bad deeds" or "evil thoughts" visited upon the soul by the gods or by one's enemies. [8]