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Likewise, it is used to calculate lipophilic efficiency in evaluating the quality of research compounds, where the efficiency for a compound is defined as its potency, via measured values of pIC 50 or pEC 50, minus its value of log P. [27] Drug permeability in brain capillaries (y axis) as a function of partition coefficient (x axis) [28]
In chemistry, the mass concentration ρ i (or γ i) is defined as the mass of a constituent m i divided by the volume of the mixture V. [1]= For a pure chemical the mass concentration equals its density (mass divided by volume); thus the mass concentration of a component in a mixture can be called the density of a component in a mixture.
Mass fraction can also be expressed, with a denominator of 100, as percentage by mass (in commercial contexts often called percentage by weight, abbreviated wt.% or % w/w; see mass versus weight). It is one way of expressing the composition of a mixture in a dimensionless size ; mole fraction (percentage by moles , mol%) and volume fraction ...
The analytical (total) concentration of a reactant R at the i th titration point is given by = + [] + where R 0 is the initial amount of R in the titration vessel, v 0 is the initial volume, [R] is the concentration of R in the burette and v i is the volume added. The burette concentration of a reactant not present in the burette is taken to be ...
The molality of a solution does not change with , since it refers to the mass of the solvent. In contrast, the concentration does change with , since the density of a solution and thus its volume are temperature-dependent. Defining the aqueous-phase composition via molality has the advantage that any temperature dependence of the Henry's law ...
When expressed in percent, it is known as the mole percent or molar percentage (unit symbol %, sometimes "mol%", equivalent to cmol/mol for 10 −2). The mole fraction is called amount fraction by the International Union of Pure and Applied Chemistry (IUPAC) [ 1 ] and amount-of-substance fraction by the U.S. National Institute of Standards and ...
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where A and B are reactants C is a product a, b, and c are stoichiometric coefficients,. the reaction rate is often found to have the form: = [] [] Here is the reaction rate constant that depends on temperature, and [A] and [B] are the molar concentrations of substances A and B in moles per unit volume of solution, assuming the reaction is taking place throughout the volume of the ...