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The κ-opioid receptor or kappa opioid receptor, abbreviated KOR or KOP for its ligand ketazocine, is a G protein-coupled receptor that in humans is encoded by the OPRK1 gene. The KOR is coupled to the G protein G i /G 0 and is one of four related receptors that bind opioid -like compounds in the brain and are responsible for mediating the ...
Cohen's kappa measures the agreement between two raters who each classify N items into C mutually exclusive categories. The definition of is =, where p o is the relative observed agreement among raters, and p e is the hypothetical probability of chance agreement, using the observed data to calculate the probabilities of each observer randomly selecting each category.
One notable example of this method is the folktale of a farmer who promises his daughter's hand in marriage to a kappa in return for the creature irrigating his land. The farmer's daughter challenges the kappa to submerge several gourds in water. When the kappa fails in its task, it retreats, saving the farmer's daughter from the marriage. [15]
Fleiss' kappa is a generalisation of Scott's pi statistic, [2] a statistical measure of inter-rater reliability. [3] It is also related to Cohen's kappa statistic and Youden's J statistic which may be more appropriate in certain instances. [4]
Kappa Alpha Psi was founded on January 5, 1911, at Indiana University Bloomington in Bloomington, Indiana. The campus of Indiana University at that time did not encourage the assimilation of Blacks. The campus of Indiana University at that time did not encourage the assimilation of Blacks.
Examples of such compounds include nalorphine and levallorphan. However, the analgesic effects from these specific drugs are limited and tend to be accompanied by dysphoria, most likely due to additional agonist action at the κ-opioid receptor.
The denticity of a ligand is described with the Greek letter κ ('kappa'). [3] For example, κ 6-EDTA describes an EDTA ligand that coordinates through 6 non-contiguous atoms. Denticity is different from hapticity because hapticity refers exclusively to ligands where the coordinating atoms are contiguous. In these cases the η ('eta') notation ...
Variant kappa Greek word καί written with a handwritten variant of kappa, from the Byzantine period. Kappa (/ ˈ k æ p ə /; [1] uppercase Κ, lowercase κ or cursive ϰ; Greek: κάππα, káppa) is the tenth letter of the Greek alphabet, representing the voiceless velar plosive IPA: sound in Ancient and Modern Greek.