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Fibrodysplasia ossificans progressiva (/ ˌ f aɪ b r oʊ d ɪ ˈ s p l eɪ ʒ (i) ə ɒ ˈ s ɪ f ɪ k æ n z p r ə ˈ ɡ r ɛ s ɪ v ə /; [1] abbr. FOP), also called Münchmeyer disease or formerly myositis ossificans progressiva, is an extremely rare connective tissue disease in which fibrous connective tissue such as muscle, tendons, and ligaments turn into bone tissue (ossification).
The disease is characterized by slowly progressive weakness and wasting of both proximal muscles (located on or close to the torso) and distal muscles (close to hands or feet), most apparent in the finger flexors and knee extensors. [3] IBM is often confused with an entirely different class of diseases, called hereditary inclusion body ...
Myositis is a rarely-encountered medical condition characterized by inflammation affecting the muscles. [2] The manifestations of this condition may include skin issues, muscle weakness, and the potential involvement of other organs. [3]
Polymyositis and the associated inflammatory myopathies have an associated increased risk of cancer. [3] The features they found associated with an increased risk of cancer were older age, age greater than 45, male sex, difficulty swallowing, death of skin cells, cutaneous vasculitis, rapid onset of myositis (<4 weeks), elevated creatine kinase, higher erythrocyte sedimentation rate and higher ...
In anatomy, a sesamoid bone (/ ˈ s ɛ s əm ɔɪ d /) [1] [2] is a bone embedded within a tendon or a muscle. [3] Its name is derived from the Greek word for 'sesame seed', indicating the small size of most sesamoids. Often, these bones form in response to strain, [4] or can be present as a normal variant. The patella is the
The tarsometatarsal joints (Lisfranc joints) are arthrodial joints in the foot. The tarsometatarsal joints involve the first, second and third cuneiform bones, the cuboid bone and the metatarsal bones. The eponym of Lisfranc joint is 18th–19th-century surgeon and gynecologist Jacques Lisfranc de St. Martin. [1]
Bursitis is the inflammation of one or more bursae (synovial sacs) of synovial fluid in the body. They are lined with a synovial membrane that secretes a lubricating synovial fluid. [1] There are more than 150 bursae in the human body. [1] The bursae rest at the points where internal functionaries, such as muscles and tendons, slide across bone ...
Enthesitis is inflammation of the entheses (singular: enthesis), the sites where tendons, ligaments and joint capsules attach to bones. [1] [2] It is a type of enthesopathy, meaning any pathologic condition of the entheses, with or without inflammation. There are some cases of isolated, primary enthesitis which are very poorly studied and ...