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Haemophilia (British English), or hemophilia (American English) [6] (from Ancient Greek αἷμα (haîma) 'blood' and φιλία (philía) 'love of'), [7] is a mostly inherited genetic disorder that impairs the body's ability to make blood clots, a process needed to stop bleeding.
Joint capsule. Haemophilia A's phenotype has a quite wide range of symptoms encompassing both internal and external bleeding episodes. Individuals with more severe haemophilia tend to experience more intense and frequent bleeding, whereas those with mild haemophilia typically exhibit milder symptoms unless subjected to surgical procedures or significant trauma.
Acquired haemophilia A (AHA) is a rare but potentially life-threatening bleeding disorder characterized by autoantibodies directed against coagulation factor VIII.These autoantibodies constitute the most common spontaneous inhibitor to any coagulation factor and may induce spontaneous bleeding in patients with no previous history of a bleeding disorder.
X chromosome. The factor IX gene is located on the X chromosome (Xq27.1-q27.2). It is an X-linked recessive trait, which explains why males are affected in greater numbers. [9] [10] A change in the F9 gene, which makes blood clotting factor IX (9), causes haemophilia B. [11]
In 2016, the NHF began recognizing March as Bleeding Disorders Awareness Month to raise awareness of hemophilia and von Willebrand disease among stakeholders. [9] Also in 2016, as part of the foundation's awareness efforts, it started the Red Tie Campaign, with the symbol representing blood and the community coming together to help those with ...
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World Hemophilia Day is held annually on April 17 by the WFH. [11] It is an awareness day for hemophilia and other bleeding disorders, [12] which also serves to raise funds and attract volunteers for the WFH. [13] It was started in 1989; April 17 was chosen in honor of Frank Schnabel's birthday. [14] [15]
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