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prednisolone – glucocorticoid (steroid) used in the management of inflammation and auto-immune disease, primarily in cats; prednisone – glucocorticoid (steroid) used in the management of inflammation and auto immune disease; pregabalin – neuropathic pain reliever and anti-convulsant; propofol – short acting intravenous drug used to ...
Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Pradofloxacin, sold under the brand name Veraflox among others, is a third-generation enhanced spectrum veterinary antibiotic of the fluoroquinolone class. [5] It was developed by Elanco Animal Health GmbH and received approval from the European Commission in April 2011, for prescription-only use in veterinary medicine for the treatment of bacterial infections in dogs and cats.
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Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.
Nitrofurazone is indicated for topical use in dogs, cats, and horses, for the treatment or prophylactic treatment of superficial bacterial infections, burns, and cutaneous ulcers. [9] Preparations for treating infections, such as fin rot , in ornamental fish are also still commercially available.
Feline idiopathic cystitis begins as an acute non-obstructive episode and is self-limiting in about 85% of cases, resolving itself in a week. In approximately 15% of cases, it can escalate into an obstructive episode ("blocked cat") which can be life-threatening for a male cat. [5]
Prednisone is a prodrug and must be converted to prednisolone by the liver before it becomes active. [6] [7] Prednisolone then binds to glucocorticoid receptors, activating them and triggering changes in gene expression. [4] Prednisone was patented in 1954 and approved for medical use in the United States in 1955.
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