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Haplogroup C-M217 is the only variety of Haplogroup C-M130 to be found among Native Americans, among whom it reaches its highest frequency in Na-Dené populations. It would also make sense that this lineage may have originated in the Americas as that is the only Variety found amongst the aboriginal population.
Haplogroup C is believed to have arisen in East Asia [4] some 24,000 years before present. It is a descendant of the haplogroup M.Haplogroup C shares six mutations downstream of the MRCA of haplogroup M with haplogroup Z and five mutations downstream of the MRCA of haplogroup M with other members of haplogroup M8.
According to ISOGG's Y-DNA haplogroup tree (2007), haplogroup C2 is defined by M38 and it has two parallel subclades, C2a-P33 and C2b-M208. However, according to Cox et al.,
Haplogroup C-M217, also known as C2 (and previously as C3), [1] is a Y-chromosome DNA haplogroup.It is the most frequently occurring branch of the wider Haplogroup C (M130). ). It is found mostly in Central Asia, Eastern Siberia and significant frequencies in parts of East Asia and Southeast Asia including some populations in the Caucasus, Middle East, South Asia, East Eur
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A haplotype is a group of alleles in an organism that are inherited together from a single parent, [1] [2] and a haplogroup (haploid from the Greek: ἁπλοῦς, haploûs, "onefold, simple" and English: group) is a group of similar haplotypes that share a common ancestor with a single-nucleotide polymorphism mutation. [3]
There is a debate concerning the geographical origins of Haplogroup M and its sibling haplogroup N. Both lineages are thought to have been the main surviving lineages involved in the out of Africa migration (or migrations) because all indigenous lineages found outside Africa belong to haplogroup M or haplogroup N. Scientists are unsure whether the mutations that define haplogroups M and N ...
Macro-haplogroup R is found mostly in Europe, Northern Africa, the Pacific and parts of Asia and the Americas. Its descendants are haplogroup R, haplogroup B, haplogroup F, haplogroup H, haplogroup V, haplogroup J, haplogroup T, haplogroup U and haplogroup K