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A collage of JSRV-infected sheep lung tumors. Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV).
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" (jaag) and "sickness" (siekte), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep.
In addition to lambs and other attendant sheep, the station has a base flock of 3,000 mature sheep. [2] Breeds developed at the U.S. Sheep Experiment Station include: The Columbia, a dual-purpose breed and one of the first originating in the U.S. Early crosses were made in Wyoming, but the originating flock was moved to the USSES in 1918.
The disease, enzootic nasal adenocarcinoma is common in North America and is found in sheep and goats on every continent except New Zealand and Australia. [5] There are more than 27 betaretroviruses similar to ENVT and JSRV in the ovine genome. [6] [7] In the future, research on ENTV may become important in studying viruses that cause human ...
Flystrike in sheep is a myiasis condition in which domestic sheep are infected by one of several species of flies that are external parasites of sheep. Sheep are particularly susceptible to flystrike because their thick wool, if sufficiently contaminated with urine and faecal material, can provide effective breeding ground for maggots even in the relative absence of wounds.
Navajo-Churro sheep at the San Francisco Zoo with four horns. Churros are small sheep with long, thin tails, horizontal ears, [1] and a double coat. Ewes are 40–60 kg (88–132 lb), while rams are 55–85 kg (121–187 lb). The sheep are long-lived and can be productive for up to 15 years. [2]
Congenital pulmonary airway malformation (CPAM), formerly known as congenital cystic adenomatoid malformation (CCAM), is a congenital disorder of the lung similar to bronchopulmonary sequestration. In CPAM, usually an entire lobe of lung is replaced by a non-working cystic piece of abnormal lung tissue.