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Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
Dry skin and dry eyes are also common. Itching occurs in 20–70% of cases, [4] and can develop at any stage of the disease. Textbooks tend to describe itching in the feet and hands, but patients may also experience itching of the scalp, face, back, or other areas. The itching is typically mild-to-moderate in intensity.
Typically, the itching is localized to the palms of the hands and soles of the feet, but can be anywhere on the body. Hallmarks of ICP include the following symptoms: [5] Most common: Itching, in particular but not limited to that of the palms of the hands and soles of the feet, without presence of a rash; Itching that is more noticeable in the ...
A pimple- or blister-like rash on or around the genitals, anus, hands, feet, chest, face or mouth that may be itchy or painful. The rash will go through stages, including scabbing and eventually ...
Affected individuals may have no symptoms or may experience signs and symptoms of liver disease, such as yellow discoloration of the skin and eyes, itching, and abdominal pain. The bile duct scarring that occurs in PSC narrows the ducts of the biliary tree and impedes the flow of bile to the intestines.
If it is felt all over the body, then it is called generalized itch or generalized pruritus. [4] Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called chronic itch or chronic pruritus.
Although the exact cause of PN is unknown, PN is associated with other dermatologic conditions such as untreated or severe atopic dermatitis and systemic causes of pruritus including liver disease and end stage kidney disease. [2] The goal of treatment in PN is to decrease itching. PN is also known as Hyde prurigo nodularis, or Picker's nodules ...
Seek professional medical help if you are experiencing incessant itchy palms. Potential medical interpretations of itchy palms include: Eczema. Psoriasis. Allergies. Diabetes. Cirrhosis. Nerve ...