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A papilloma (plural papillomas or papillomata) (papillo-+ -oma) is a benign epithelial tumor [1] growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).
HPV is the most common sexually transmitted infection (STI), globally. [5] High-risk HPVs cause about 5% of all cancers worldwide and about 37,300 cases of cancer in the United States each year. [10] Cervical cancer is among the most common cancers worldwide, causing an estimated 604,000 new cases and 342,000 deaths in 2020. [1]
Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. [1] Several hundred species of papillomaviruses, traditionally referred to as "types", [2] have been identified infecting all carefully inspected mammals, [2] but also other vertebrates such as birds, snakes, turtles and fish.
Squamous cell papilloma of the mouth or throat is generally diagnosed in people between the ages of 30 and 50, [1] and is normally found on the inside of the cheek, on the tongue, or inside of lips. Oral papillomas are usually painless, and not treated unless they interfere with eating or are causing pain. [ 1 ]
According to the World Health Organization, "cervical cancer is the fourth most common cancer in women." An estimated 660,000 women were diagnosed with the cancer worldwide in 2022, and 350,000 ...
Many HPV types can produce a benign growth, often called a "wart" or "papilloma", in the area they infect. [10] Many of the more common HPV and wart types are listed below. Common warts – HPV types 2 and 4 (most common); also types 1, 3, 26, 29, and 57 and others.
A common symptom of laryngeal papillomatosis is a change in voice quality. More specifically, hoarseness is observed. [4] [5] As a consequence of the narrowing of the laryngeal or tracheal parts of the airway, shortness of breath, chronic cough and stridor (i.e. noisy breathing which can sound like a whistle or a snore), can be present.
Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in humans. [1] They result from abnormal proliferation of the epithelial cells lining the breast ducts. [2] Two types of intraductal papillomas are generally distinguished. The central type develops near the nipple.