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A papilloma (plural papillomas or papillomata) (papillo-+ -oma) is a benign epithelial tumor [1] growing exophytically (outwardly projecting) in nipple-like and often finger-like fronds. In this context, papilla refers to the projection created by the tumor, not a tumor on an already existing papilla (such as the nipple).
Between 60% and 90% of the other cancers listed above are also linked to HPV. [7] HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis. [1] An HPV infection is caused by the human papillomavirus, a DNA virus from the papillomavirus family. [8] [9] Over 200 types have been described. [10]
Squamous cell papilloma of the mouth or throat is generally diagnosed in people between the ages of 30 and 50, [1] and is normally found on the inside of the cheek, on the tongue, or inside of lips. Oral papillomas are usually painless, and not treated unless they interfere with eating or are causing pain. [ 1 ]
Papillomaviridae is a family of non-enveloped DNA viruses whose members are known as papillomaviruses. [1] Several hundred species of papillomaviruses, traditionally referred to as "types", [2] have been identified infecting all carefully inspected mammals, [2] but also other vertebrates such as birds, snakes, turtles and fish.
Laryngeal papillomatosis, also known as recurrent respiratory papillomatosis (RRP) or glottal papillomatosis, is a rare medical condition in which benign tumors form along the aerodigestive tract. [1] [2] There are two variants based on the age of onset: juvenile and adult laryngeal papillomatosis. [3]
[1] [2] PB is also termed juvenile papillomatosis because of its frequent occurrence in younger women (including, in uncommon cases, children and adolescent females) and Swiss cheese disease because of its microscopic appearance. [3] Rarely, PB has also been diagnosed in very young, adolescent, and adult males. [4]
Intraductal papillomas of the breast are benign lesions with an incidence of approximately 2-3% in humans. [1] They result from abnormal proliferation of the epithelial cells lining the breast ducts. [2] Two types of intraductal papillomas are generally distinguished. The central type develops near the nipple.
Malignant acanthosis nigricans may also become evident, many times with the sudden eruption of multiple seborrheic keratoses, known as the sign of Leser-Trélat. [ 9 ] [ 10 ] [ 11 ] Florid cutaneous papillomatosis mandates a search for an underlying malignancy, recognizing that it may be seen in patients with multiple visceral carcinomas.