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There are intensely itchy spots on the central back, mid chest and occasionally elsewhere. Frequently, it follows sweating or some unexpected heat stress. The itchy eruption lasts an average of 10–12 months. It is characterized by papules and papulovesicles with excoriations occurring on the chest, back, lower sternum, arms, and thighs. [4]
Acantholysis is the loss of intercellular connections, such as desmosomes, resulting in loss of cohesion between keratinocytes, [1] seen in diseases such as pemphigus vulgaris. [2] It is absent in bullous pemphigoid , making it useful for differential diagnosis .
Image at right shows influx of inflammatory cells including eosinophils and neutrophils in the dermis (solid arrow) and blister cavity (dashed arrows), and deposition of fibrin (asterisks). [15] However, the diagnosis of bullous pemphigoid consist of at least 2 positive results out of 3 criteria: [19] Pruritus and/or predominant cutaneous blisters
Waddell's signs are not considered a de facto indicator of deception for the purpose of financial gain. [6] In a 2003 review, Fishbain, et al. stated that Waddell's signs do not reliably distinguish organic from psychological pain but instead tend to underestimate the amount of pain that is actually experienced. [7]
tenderness in the right lower quadrant increases when the patient moves from the supine position to a recumbent posture on the left side Rossolimo's sign: Grigory Ivanovich Rossolimo: neurology: pyramidal tract lesions: The Babinski sign – a reappraisal Neurol India 48 (4): 314–8. percussion of the tips of the toes causes exaggerated ...
Symptoms for spinal tumors may vary due to factors such as the type of tumor, the region of the spine, and the health of the patient. Back pain is the most common symptom and it can be a problem if the pain is severe, has a time frame that lasts longer than it would for a normal injury, and becomes worse while laying down or at rest.
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [ 2 ] such as the posterior and lateral folds of the neck , the armpits , groin , navel , forehead and other areas.
Note the intercellular IgG deposits in the epidermis and the early intraepidermal vesicle caused by acantholysis. Pemphigus (/ ˈ p ɛ m f ɪ ɡ ə s / or / p ɛ m ˈ f aɪ ɡ ə s /) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. [1] The name is derived from the Greek root pemphix, meaning "blister ...
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