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Mange (/ ˈ m eɪ n dʒ /) is a type of skin disease caused by parasitic mites. [1] Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals.
Moxidectin was approved for onchocerciasis (river-blindness) in 2018 for people over the age of 11 in the United States based on two studies. [5] There is a need for additional trials, with long-term follow-up, to assess whether moxidectin is safe and effective for treatment of nematode infection in children and women of childbearing potential. [6]
A more direct way of treating some types of mite are antiparasitic drugs that act systemically through the internal circulation of the animal rather than topically on the skin. The avermectin drugs such as ivermectin are used as acaricides against deeply feeding mites such as Sarcoptes and Demodex species. The drugs are delivered orally or ...
Psoroptes mites are responsible for causing psoroptic mange in various animals, leading to economic losses among farmers of cattle, sheep and goats. [1] It is also known as sheep scab and cattle scab. [1] The disease is highly infectious, and is transmitted via fenceposts and other structures that livestock use when scratching themselves. [1]
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
It is also indicated for the treatment and control of intestinal roundworms (Toxocara canis and Toxascaris leonina), hookworms (Ancylostoma caninum and Uncinaria stenocephala), and whipworms (Trichuris vulpis).
A longtime anti-vaxxer, Robert F. Kennedy Jr. vowed to "Make America Healthy Again" if he is confirmed as Trump's Health and Human Services Secretary.
Demodectic mange with secondary infection is treated with antibiotics and medicated shampoos. For more severe generalized cases, Amitraz is a parasiticidal dip that is licensed for use in many countries (the only FDA approved treatment in the USA) for treating canine demodicosis. It is applied weekly or biweekly for several weeks, until no ...