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Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear There is a wide range of ototoxic medications, for example, antibiotics , antimalarials , chemotherapeutic agents , non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics . [ 2 ]
Ototoxic drugs also may cause subjective tinnitus, as they may cause hearing loss, [15] or increase the damage done by exposure to loud noise. [39] This damage may occur even at doses not considered ototoxic. [40] More than 260 medications have been reported to cause tinnitus as a side effect. [41]
At high doses, quinine, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug. [20] Erectile dysfunction medications may have the potential to cause hearing loss. [36] However the link between erectile dysfunction medications and hearing loss remains ...
That ringing or buzzing in your ears at any given time is a symptom commonly known as tinnitus. ... Treatment for tinnitus does vary however, depending on the cause. Tinnitus retraining therapy is ...
For example, very curvy ear canals, narrow ear canals, or surgical ears are more prone to earwax buildup. When wax builds up, it causes muffled hearing, tinnitus, or aural fullness (plugged-up ...
Some medications cause irreversible damage to the ear, and are limited in their use for this reason. The most important group is the aminoglycosides (main member gentamicin). A rare mitochondrial mutation, m.1555A>G, can increase an individual's susceptibility to the ototoxic effect of aminoglycosides.
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