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Marked atypia of type 2 pneumocytes is a characteristic finding in association with treatment with busulfan and other chemotherapeutic agents.. Atypia (from Greek, a + typos, without type; a condition of being irregular or nonstandard) [1] is a histopathologic term for a structural abnormality in a cell, i.e. it is used to describe atypical cells.
Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.
Nuclear atypia refers to abnormal appearance of cell nuclei. It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic. Nuclear atypia can be seen in reactive changes, pre-neoplastic changes and malignancy. Severe nuclear atypia is, in most cases, considered an indicator of malignancy.
Atypical bacteria are bacteria that do not get colored by gram-staining but rather remain colorless: they are neither Gram-positive nor Gram-negative. These include the Chlamydiaceae , Legionella and the Mycoplasmataceae (including mycoplasma and ureaplasma ); the Spirochetes and Rickettsiaceae are also often considered atypical.
ThinPrep pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus (HPV). [1]
In literature the term atypical pneumonia is current, sometimes contrasted with viral pneumonia (see above) and sometimes, though incorrectly, with bacterial pneumonia. Many of the organisms causative of atypical pneumonia are unusual types of bacteria (Mycoplasma is a type of bacteria without a cell wall and Chlamydias are intracellular ...
atypical squamous cells ASCA: anti–Saccharomyces cerevisiae antibodies: ASC-H: atypical squamous cells—cannot exclude HSIL: ASCAD: arteriosclerotic coronary artery disease: ASCUS ASC-US: atypical squamous cells of undetermined significance: ASCVD: arteriosclerotic vascular disease (arteriosclerosis) ASD: atrial septal defect autism spectrum ...
SOX10 immunohistochemistry of normal skin (top) and atypical melanocytic proliferation (bottom), seen mainly in hair follicles. SOX10 immunohistochemistry facilitates showing lentigo maligna , as an increased number of melanocytes along stratum basale and nuclear pleumorphism .