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Pagetoid is a term used in dermatology to refer to "upward spreading" of abnormal cells in the epidermis (ie from bottom to top). It is uncommon and a possible indication of a precancerous or cancerous condition. Cells display pagetoid growth when they invade the upper epidermis from below.
Many skin conditions require a skin biopsy for confirmation of the diagnosis. With several of these conditions there are features within the cells contained in the skin biopsy specimen that have elements in their cytoplasm or nucleus that have a characteristic appearance unique to the condition.
Atypical fibroxanthoma (AFX) of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically. [ 2 ] : 613 Atypical fibroxanthoma manifests as a hard, pink or red papule or nodule that grows over the course of several months and may bleed or ulcerate .
Similar to mycosis fungoides, with bandlike infiltrate and epidermotropism of smaller atypical lymphocytes that may be CD30-. C Similar to cutaneous anaplastic large-cell lymphoma , with larger clusters or sheets of large anaplastic CD30+ cells without the interspersed mixed infiltrate of Type A.
A dysplastic nevus or atypical mole is a nevus (mole) whose appearance is different from that of common moles. In 1992, the NIH recommended that the term "dysplastic nevus" be avoided in favor of the term "atypical mole". [ 1 ]
Marked atypia of type 2 pneumocytes is a characteristic finding in association with treatment with busulfan and other chemotherapeutic agents.. Atypia (from Greek, a + typos, without type; a condition of being irregular or nonstandard) [1] is a histopathologic term for a structural abnormality in a cell, i.e. it is used to describe atypical cells.
Download as PDF; Printable version; ... Dermatology: Atypical lichen myxedematosus is a skin condition caused by fibroblasts producing abnormally large amounts of ...
Dysplastic nevus (atypical mole, atypical nevus, B-K mole, Clark's nevus, dysplastic melanocytic nevus, nevus with architectural disorder) Dysplastic nevus syndrome (B-K mole syndrome, familial atypical multiple mole–melanoma syndrome, familial melanoma syndrome) Ephelis (freckle) Epithelioid blue nevus; Generalized lentiginosis