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  2. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Motor neuron diseases affect both children and adults. [5] While each motor neuron disease affects patients differently, they all cause movement-related symptoms, mainly muscle weakness. [6] Most of these diseases seem to occur randomly without known causes, but some forms are inherited. [2]

  3. Juvenile primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Juvenile_Primary_Lateral...

    Mutations in the ALS2 gene in this disorder disrupt the instructions for producing alsin. As a result, alsin is unstable and decays rapidly, or it is disabled and cannot function properly. It is currently unknown how the loss of functional alsin protein causes the death of motor neurons and the symptoms of juvenile primary lateral sclerosis. [1]

  4. Motor disorder - Wikipedia

    en.wikipedia.org/wiki/Motor_disorder

    Motor disorders are disorders of the nervous system that cause abnormal and involuntary movements. They can result from damage to the motor system. [1]Motor disorders are defined in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) – published in 2013 to replace the fourth text revision – as a new sub-category of neurodevelopmental disorders.

  5. Gerstmann syndrome - Wikipedia

    en.wikipedia.org/wiki/Gerstmann_syndrome

    Gerstmann syndrome is a neurological disorder that is characterized by a constellation of symptoms [1] that suggests the presence of a lesion usually near the junction of the temporal and parietal lobes at or near the angular gyrus.

  6. ALS - Wikipedia

    en.wikipedia.org/wiki/ALS

    Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or (in the United States) Lou Gehrig's disease (LGD), is a rare, terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction. [3]

  7. Basal ganglia disease - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia_disease

    Of all the circuits, the motor circuit is the most studied due its importance to motor disorders. The direct pathway of the motor circuit is one in which projections from the cortex travel to the putamen directly to the internal segment of the globus pallidus (GPi also known as GP-Medial) or the substantia nigra, pars reticulata (SNr) and are then directed toward the ventral anterior nucleus ...

  8. Subacute combined degeneration of spinal cord - Wikipedia

    en.wikipedia.org/wiki/Subacute_combined...

    Prolonged deficiency of vitamin B 12 leads to irreversible nervous system damage. HIV-associated vacuolar myelopathy can present with a similar pattern of dorsal column and corticospinal tract demyelination. [citation needed] It has been thought that if someone is deficient in vitamin B 12 and folic acid, the vitamin B 12 deficiency must

  9. Lateral corticospinal tract - Wikipedia

    en.wikipedia.org/wiki/Lateral_corticospinal_tract

    The lateral corticospinal tract (also called the crossed pyramidal tract or lateral cerebrospinal fasciculus) is the largest part of the corticospinal tract. It extends throughout the entire length of the spinal cord , and on transverse section appears as an oval area in front of the posterior column and medial to the posterior spinocerebellar ...

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