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The U.S. Food and Drug Administration has approved Pfizer's newest drug on the migraine market, Zavzpret (zavegepant) -- the first and only migraine treatment of its kind to be offered in nasal spray.
Zavegepant, sold under the brand name Zavzpret, is a medication used for the treatment of migraine. [1] Zavegepant is a calcitonin gene-related peptide receptor antagonist. [1] It is sprayed into the nose. [1] It is sold by Pfizer. [1] The most common adverse reactions include taste disorders, nausea, nasal discomfort, and vomiting. [1]
Drug marks ‘significant breakthrough’ for people with migraine who need freedom from pain
Ubrogepant is approved for acute treatment of migraines [7] [4] Rimegepant (BMS-927711) is approved for acute and preventative treatment of migraines [8] [3] Atogepant (AGN-241689) is approved for preventative treatment of migraines [5] Zavegepant (BHV- 3500) is a nasal spray approved for acute treatment of migraines. [9] [10]
Zavzpret is a new nasal spray to treat migraine headaches in adults. But how does the medication work and who should try the new FDA-approved medication?
Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...
She said, “we are over the moon” about the FDA's approval of the spray, which Zacky will start carrying when it becomes available. First marketed in 1901, epinephrine predates the FDA itself. Products like the EpiPen auto-injector, approved in 1987, were authorized based on chemistry and manufacturing data and were not required to prove ...
In a surprise to its makers, a nasal spray intended to be an alternative to the EpiPen was sent back by the FDA, the company announced.
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