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Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV).
JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" (jaag) and "sickness" (siekte), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep.
Sheep and goats are both small ruminants with cosmopolitan distributions due to their being kept historically and in modern times as grazers both individually and in herds in return for their production of milk, wool, and meat. [1] As such, the diseases of these animals are of great economic importance to humans.
The disease, enzootic nasal adenocarcinoma is common in North America and is found in sheep and goats on every continent except New Zealand and Australia. [5] There are more than 27 betaretroviruses similar to ENVT and JSRV in the ovine genome. [6] [7] In the future, research on ENTV may become important in studying viruses that cause human ...
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Sheep farming in Namibia (2017). According to the FAOSTAT database of the United Nations Food and Agriculture Organization, the top five countries by number of head of sheep (average from 1993 to 2013) were: mainland China (146.5 million head), Australia (101.1 million), India (62.1 million), Iran (51.7 million), and the former Sudan (46.2 million). [2]
Scrapie and other transmissible spongiform encephalopathies are caused by prions. [19] Prions were determined to be the infectious agent because transmission is difficult to prevent with heat, radiation and disinfectants, the agent does not evoke any detectable immune response, and it has a long incubation period of between 18 months and 5 years. [20]