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Ovine pulmonary adenocarcinoma (OPA), also known as ovine pulmonary adenomatosis, or jaagsiekte, is a chronic and contagious disease of the lungs of sheep and goats. OPA is caused by a retrovirus called jaagsiekte sheep retrovirus (JSRV).
Nairobi sheep disease orthonairovirus (NSDV) infection; orf, also known as contagious ecthyma, contagious pustular dermatitis, infectious labial dermatitis, thistle disease, sore mouth, or scabby mouth; ovine encephalomyelitis (louping ill) ovine progressive pneumonia (OPP) ovine pulmonary adenocarcinoma
JSRV is the virus that is the cause of the contagious lung tumors in sheep called ovine pulmonary adenocarcinoma (OPA). The disease has also been called "jaagsiekte", after the Afrikaans words for "chase" (jaag) and "sickness" (siekte), to describe the respiratory distress observed in an animal out of breath from being chased, indicating the breathing difficulty experienced by infected sheep.
The disease, enzootic nasal adenocarcinoma is common in North America and is found in sheep and goats on every continent except New Zealand and Australia. [5] There are more than 27 betaretroviruses similar to ENVT and JSRV in the ovine genome. [6] [7] In the future, research on ENTV may become important in studying viruses that cause human ...
Scrapie and other transmissible spongiform encephalopathies are caused by prions. [19] Prions were determined to be the infectious agent because transmission is difficult to prevent with heat, radiation and disinfectants, the agent does not evoke any detectable immune response, and it has a long incubation period of between 18 months and 5 years. [20]
In addition to lambs and other attendant sheep, the station has a base flock of 3,000 mature sheep. [2] Breeds developed at the U.S. Sheep Experiment Station include: The Columbia, a dual-purpose breed and one of the first originating in the U.S. Early crosses were made in Wyoming, but the originating flock was moved to the USSES in 1918.
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Pulmonary function: increased residual volume, increased total lung capacity, fixed obstruction, low diffusing capacity of the lung for carbon monoxide that corrects with alveolar volume High-resolution CT scan: diffuse pulmonary nodules 4–10 mm, greater than 20 nodules, mosaic attenuation or air trapping in greater than 50% of the lung