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Treatments include a series of reduced-breathing exercises that focus on nasal-breathing, breath-holding and relaxation. Advocates of the Buteyko method claim that it can alleviate symptoms and reliance on medication for patients with asthma, chronic obstructive pulmonary disease (COPD), and chronic hyperventilation.
The investigators then obtain a standard set of clinical observations on each patient and a test or clinical follow-up to define the true state of the patient. They then use statistical methods to identify the best clinical predictors of the patient's true state. The probability of disease will depend on the patient's key clinical predictors.
In a clinical study, bronchial thermoplasty has been proven to provide long-term reduction in asthma induced breathing difficulty to at least 5 years and improve the quality of life for severe persistent asthma patients. [7] Reduction in asthma attacks, ER visits, and hospitalizations for respiratory symptoms are maintained to at least 5 years ...
A clinical formulation, also known as case formulation and problem formulation, is a theoretically-based explanation or conceptualisation of the information obtained from a clinical assessment. It offers a hypothesis about the cause and nature of the presenting problems and is considered an adjunct or alternative approach to the more ...
In the same year, Larry E. Beutler and colleagues published their systematic treatment selection model, which attempted to integrate common and specific factors into a single model that therapists could use to guide treatment, considering variables of patient dimensions, environments, settings, therapist dimensions, and treatment types. [22]
Causal Inference has also been used for treatment effect estimation. Assuming a set of observable patient symptoms(X) caused by a set of hidden causes(Z) we can choose to give or not a treatment t. The result of the giving or not giving the treatment is the effect estimation y. If the treatment is not guaranteed to have a positive effect then ...
Rubin defines a causal effect: Intuitively, the causal effect of one treatment, E, over another, C, for a particular unit and an interval of time from to is the difference between what would have happened at time if the unit had been exposed to E initiated at and what would have happened at if the unit had been exposed to C initiated at : 'If an hour ago I had taken two aspirins instead of ...
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.