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Glucose + 2 NAD + + 2 P i + 2 ADP → 2 pyruvate + 2 NADH + 2 ATP + 2 H + + 2 H 2 O + energy. Starting with glucose, 1 ATP is used to donate a phosphate to glucose to produce glucose 6-phosphate. Glycogen can be converted into glucose 6-phosphate as well with the help of glycogen phosphorylase.
The anaerobic glycolysis (lactic acid) system is dominant from about 10–30 seconds during a maximal effort. It produces 2 ATP molecules per glucose molecule, [3] or about 5% of glucose's energy potential (38 ATP molecules). [4] [5] The speed at which ATP is produced is about 100 times that of oxidative phosphorylation. [1]
d -Glucose + 2 [NAD] + + 2 [ADP] + 2 [P] i 2 × Pyruvate 2 × + 2 [NADH] + 2 H + + 2 [ATP] + 2 H 2 O Glycolysis pathway overview The use of symbols in this equation makes it appear unbalanced with respect to oxygen atoms, hydrogen atoms, and charges. Atom balance is maintained by the two phosphate (P i) groups: Each exists in the form of a hydrogen phosphate anion, dissociating to contribute ...
Values over 180 mg/dL in venous whole blood are pathological and are termed hyperglycemia, values below 40 mg/dL are termed hypoglycaemia. [120] When needed, glucose is released into the bloodstream by glucose-6-phosphatase from glucose-6-phosphate originating from liver and kidney glycogen, thereby regulating the homeostasis of blood glucose ...
The hydroxyl on carbon 1 of glucose 6-phosphate turns into a carbonyl, generating a lactone, and, in the process, NADPH is generated. 6-phosphoglucono-δ-lactone + H 2 O: → 6-phosphogluconate + H + 6-phosphogluconolactonase: Hydrolysis: 6-phosphogluconate + NADP + → ribulose 5-phosphate + NADPH + CO 2: 6-phosphogluconate dehydrogenase ...
Within aerobic respiration, the P/O ratio continues to be debated; however, current figures place it at 2.5 ATP per 1/2(O 2) reduced to water, though some claim the ratio is 3. [5] This figure arises from accepting that 10 H + are transported out of the matrix per 2 e −, and 4 H + are required to move inward to synthesize a molecule of ATP. [6]
Glucose reacts with oxygen in the following reaction, C 6 H 12 O 6 + 6O 2 → 6CO 2 + 6H 2 O. Carbon dioxide and water are waste products, and the overall reaction is exothermic. The reaction of glucose with oxygen releasing energy in the form of molecules of ATP is therefore one of the most important biochemical pathways found in living organisms.
Anaerobic cellular respiration and fermentation generate ATP in very different ways, and the terms should not be treated as synonyms. Cellular respiration (both aerobic and anaerobic) uses highly reduced chemical compounds such as NADH and FADH 2 (for example produced during glycolysis and the citric acid cycle) to establish an electrochemical gradient (often a proton gradient) across a membrane.