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The ED 95 is the dose required to achieve the desired effect in 95% of the population. In anaesthesia, the term ED 95 is also used when referring to the pharmacology of neuromuscular blocking drugs. In this context, it is the dose which will cause 95% depression of the height of a single muscle twitch, in half of the population.
DOTB binds with high affinity to the serotonin 5-HT 2 receptors, including to the serotonin 5-HT 2A and 5-HT 2C receptors and, to about a 10-fold lesser extent, to the serotonin 5-HT 2B receptor.
ED 95: the dose of any given intramuscular-blocking agent required to produce 95% suppression of muscle twitch (e.g., the abductor pollicis) response with balanced anesthesia; Clinical duration: difference in time between time of injection and time to 25% recovery from neuromuscular block
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This is a list of abbreviations used in medical prescriptions, including hospital orders (the patient-directed part of which is referred to as sig codes).This list does not include abbreviations for pharmaceuticals or drug name suffixes such as CD, CR, ER, XT (See Time release technology § List of abbreviations for those).
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Pharmacology is the science of drugs and medications, [1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [ 2 ]
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