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Daratumumab, sold under the brand name Darzalex among others, is an anti-cancer monoclonal antibody medication. It binds to CD38 , [ 7 ] which is overexpressed in multiple myeloma cells. [ 8 ]
Eligible participants were required to have newly diagnosed multiple myeloma and were ineligible for transplant. [2] Efficacy of daratumumab and hyaluronidase-fihj in combination with Rd (D-Rd) was evaluated in a single-arm cohort of this trial. [2] Eligible participants had received at least one prior line of therapy.
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [6] Often, no symptoms are noticed initially. [10] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [10]
J&J (JNJ) submits sBLA seeking approval for Darzalex combination regimen in newly-diagnosed, transplant eligible multiple myeloma patient population
The trial assessed Blenrep (belantamab mafodotin) in combination with bortezomib plus dexamethasone (BVd) versus Johnson & Johnson’s (NYSE:JNJ) Darzalex (daratumumab) in combination with ...
Two federal judges will consider on Friday whether Elon Musk's government cost-cutting team known as DOGE will have access to Treasury Department payment systems and potentially sensitive data at ...
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Justin Baldoni disclosed a photo of handwritten notes allegedly from his meeting with an intimacy coordinator, a meeting he claims in his lawsuit Blake Lively chose to skip.
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