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  2. Heart sounds - Wikipedia

    en.wikipedia.org/wiki/Heart_sounds

    These are the first heart sound (S 1) and second heart sound (S 2), produced by the closing of the atrioventricular valves and semilunar valves, respectively. In addition to these normal sounds, a variety of other sounds may be present including heart murmurs, adventitious sounds, and gallop rhythms S 3 and S 4.

  3. Heart valve - Wikipedia

    en.wikipedia.org/wiki/Heart_valve

    The closure of the semilunar valves causes the second heart sound. The aortic valve , which has three cusps, lies between the left ventricle and the aorta . During ventricular systole , pressure rises in the left ventricle and when it is greater than the pressure in the aorta, the aortic valve opens, allowing blood to exit the left ventricle ...

  4. Systolic heart murmur - Wikipedia

    en.wikipedia.org/wiki/Systolic_heart_murmur

    Mitral valve prolapse: This is the most common cause of late systolic murmurs. It can be heard best over the apex of the heart, usually preceded by clicks. The most common cause of mitral valve prolapse is "floppy" valve (Barlow's) syndrome. If the prolapse becomes severe enough, mitral regurgitation may occur.

  5. Phonocardiogram - Wikipedia

    en.wikipedia.org/wiki/Phonocardiogram

    Heart sounds result from vibrations created by the closure of the heart valves. There are at least two; the first (S1) is produced when the atrioventricular valves (tricuspid and mitral) close at the beginning of systole and the second (S2) when the aortic valve and pulmonary valve (semilunar valves) close at the end of systole. [4]

  6. Fourth heart sound - Wikipedia

    en.wikipedia.org/wiki/Fourth_heart_sound

    The fourth heart sound or S 4 is an extra heart sound that occurs during late diastole, immediately before the normal two "lub-dub" heart sounds (S 1 and S 2).It occurs just after atrial contraction and immediately before the systolic S 1 and is caused by the atria contracting forcefully in an effort to overcome an abnormally stiff or hypertrophic ventricle.

  7. Isovolumetric contraction - Wikipedia

    en.wikipedia.org/wiki/Isovolumetric_contraction

    The isovolumetric contraction phase lasts about 0.05 seconds, [1] but this short period of time is enough to build up a sufficiently high pressure that eventually overcomes that of the aorta and the pulmonary artery upon opening of the semilunar valves. This process, therefore, helps maintain the correct unidirectional flow of blood through the ...

  8. “Breaking Bad” Producer Worried Bob Odenkirk’s 'Silly' Saul ...

    www.aol.com/breaking-bad-producer-worried-bob...

    Gould wrote “Better Call Saul,” the episode of Breaking Bad’s second season in which Odenkirk’s character made his debut.But even then, he tells Sepinwall, he wasn’t sure Saul would have ...

  9. Wiggers diagram - Wikipedia

    en.wikipedia.org/wiki/Wiggers_diagram

    A Wiggers diagram modified from [1]. A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century.