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Entomophthora muscae is a species of pathogenic fungus in the order Entomophthorales which causes a fatal disease in flies. It can cause epizootic outbreaks of disease in houseflies and has been investigated as a potential biological control agent.
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Originally, C. coronatus was considered to be a part of the genus Boudierella, [2] however it was later transferred to the genus Conidiobolus by Saccardo and Sydow. [2] The fungus was also treated in the genus Entomophthora, [5] and the name Entomophthora coronata remains a widely used synonym. [3]
Treatment for phycomycosis is very difficult and includes surgery when possible. Postoperative recurrence is common. Antifungal drugs show only limited effect on the disease, but itraconazole and terbinafine hydrochloride are often used for two to three months following surgery. [ 4 ]
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Entomophthora is a fungal pathogenic disease. In order for this species to infect other organisms the pathogen must come in contact with the insect's body. Fungal transmission occurs through the movement of microscopic reproductive spores through the environment. These spores are released out into the environment via the rupturing of a sporangium.
Green peach aphid, Myzus persicae, killed by the fungus Pandora neoaphidis (Entomophthoromycota: Entomophthorales) Scale bar = 0.3 mm. Entomopathogenic fungi show a diversity of lifecycles, with differences across lineages, as well as within lineages, between species, and even between isolates within species. [5]
Most insects living near the soil have evolved natural defenses against entomopathogenic fungi like M. anisopliae. This fungus is, therefore, locked in an evolutionary battle to overcome these defenses, which has led to a large number of isolates (or strains ) that are adapted to certain groups of insects.