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Nephrogenic systemic fibrosis is a rare syndrome that involves fibrosis of the skin, ... History of exposure to GBCAs would favor NSF as the differential diagnosis ...
Gadodiamide is one of the main GBCA associated with nephrogenic systemic fibrosis (NSF), a toxic reaction occurring in some people with kidney problems. [6] No cases have been seen in people with normal kidney function. [7] A 2015 study found gadolinium deposited in the brain tissue of people who had received gadodiamide. [8]
Fibrosis can occur in many tissues within the body, typically as a result of inflammation or damage. Common sites of fibrosis include the lungs, liver, kidneys, brain, and heart: Micrograph showing cirrhosis of the liver. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue.
Nephrogenic diabetes insipidus is most common in its acquired forms, meaning that the defect was not present at birth. These acquired forms have numerous potential causes. The most obvious cause is a kidney or systemic disorder, including amyloidosis , [ 2 ] polycystic kidney disease , [ 3 ] electrolyte imbalance, [ 4 ] [ 5 ] or some other ...
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.
A version of this story appeared in CNN’s What Matters newsletter. To get it in your inbox, sign up for free here.. We will not know the extent or the success of President Donald Trump’s purge ...
The association of idiopathic retroperitoneal fibrosis with various immune-related conditions and response to immunosuppression led to a search for an autoimmune cause of idiopathic RPF. [5] [6] Many of these previously idiopathic cases can now be attributed to IgG4-related disease, an autoimmune disorder proposed in 2003.
The video features Otis, a 4-year-old Labrador from Leeds, England, displaying his discontent in a manner strikingly similar to a human toddler’s tantrum. As the clip begins, Otis comfortably ...