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Sex determination ban in India. Prenatal sex determination was banned in India in 1994, under the Pre-Conception and Pre-Natal Diagnostic Techniques Act, 1994. [6] The act aims to prevent sex-selective abortion, which, according to the Indian Ministry of Health and Family Welfare, "has its roots in India's long history of strong patriarchal influence in all spheres of life".
Serial quantitative blood tests may be done, usually 48 hours apart, and interpreted based on the knowledge that hCG in a viable normal pregnancy rises rapidly in early pregnancy. For example, for a starting hCG level of 1,500 mIU/ml or less, the hCG of continuing, normal pregnancy will increase at least 49% in 48 hours.
An example of an algorithm for determining the indication for prenatal genetic testing for trisomy 21 (Down syndrome), wherein the genetic blood test (in center) is performed by detecting cffDNA in a blood sample from the mother. [60] Trisomy 21. Fetal trisomy of chromosome 21 is the cause of Down's syndrome.
In general, it's best to wait until you've missed your period, and to take the test first thing in the morning. Learn how timing impacts accuracy from experts.
The AFP test is often done in the second trimester using the serum from the maternal blood draw. This test looks at a specific protein that is formed in the liver of the fetus and released into the fluid contents of the womb, which is then absorbed into the mother's blood stream. Multiple determinations stem from the results of AFP testing.
It can be performed at or after week 12 of pregnancy. At this point, 3 ⁄ 4 of fetal sexes can be correctly determined, according to a 2001 study. [56] Accuracy for males is approximately 50% and for females almost 100%. When performed after week 13 of pregnancy, ultrasonography gives an accurate result in almost 100% of cases. [56]
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