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Meso-zeaxanthin, lutein, and 3R,3′R-zeaxanthin are the main carotenoids in the macula lutea, found in a ratio of 1:1:1, and are collectively referred to as macular pigment (MP). [3] Meso-zeaxanthin is concentrated at the epicentre of the macula, where it accounts for around 50% of MP at this location, with lutein dominating the peripheral macula.
The principal natural form of zeaxanthin is (3R,3′R)-zeaxanthin. The macula mainly contains the (3R,3′R)- and meso-zeaxanthin forms, but it also contains much smaller amounts of the third (3S,3′S) form. [8] Evidence exists that a specific zeaxanthin-binding protein recruits circulating zeaxanthin and lutein for uptake within the macula. [9]
Lutein is also found in egg yolks and animal fats. Lutein is isomeric with zeaxanthin, differing only in the placement of one double bond. Lutein and zeaxanthin can be interconverted in the body through an intermediate called meso-zeaxanthin. [5] The principal natural stereoisomer of lutein is (3R,3 ′ R,6 ′ R)-beta,epsilon-carotene-3,3 ...
A review that considered berberine’s effects on heart health found some studies supporting this claim, but due to the high risk of bias, the researchers recommended more clinical trials be ...
In plants, the xanthophyll lutein is the most abundant carotenoid and its role in preventing age-related eye disease is currently under investigation. [5] Lutein and the other carotenoid pigments found in mature leaves are often not obvious because of the masking presence of chlorophyll. When chlorophyll is not present, as in autumn foliage ...
Poor sleep is also tied to several health effects, like weight gain, diabetes, and heart disease, so getting proper rest can reduce your risk. Harris notes certain behaviors associated with ...
She's inspired by naturopathic medicine, which she said involves "new age tech." Barnes-Lentz and the team at her clinic use scientific literature to "guide" what she describes as her "health ...
Astaxanthin / æ s t ə ˈ z æ n θ ɪ n / is a keto-carotenoid within a group of chemical compounds known as carotenones or terpenes. [3] [4] [5] Astaxanthin is a metabolite of zeaxanthin and canthaxanthin, containing both hydroxyl and ketone functional groups.
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