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Pegfilgrastim, sold under the brand name Neulasta among others, is a PEGylated form of the recombinant human granulocyte colony-stimulating factor (GCSF) analog filgrastim. [18] It serves to stimulate the production of white blood cells ( neutrophils ).
Common side effects include fever, cough, chest pain, joint pain, vomiting, and hair loss. [19] Severe side effects include splenic rupture and allergic reactions. [19] It is unclear if use in pregnancy is safe for the baby. [19] Filgrastim is a recombinant form of the naturally occurring granulocyte colony-stimulating factor (G-CSF). [19]
The most common side effects are fatigue, nausea, diarrhea, bone pain, headache, fever, anemia, rash, myalgia, arthralgia, and back pain. [ 4 ] Eflapegrastim was approved for medical use in the United States in September 2022.
A number of diseases can cause bone pain, including the following: Endocrine, such as hyperparathyroidism, osteoporosis, kidney failure. [7]Gastrointestinal or systemic, such as celiac disease and non-celiac gluten sensitivity (both often occur without obvious digestive symptoms), inflammatory bowel disease (including Crohn's disease and ulcerative colitis).
Efbemalenograstim alfa is an immunostimulant/colony stimulating factor that belongs to the class of hematopoietic growth factors (granulocyte colony stimulating factor; G CSF) which increase the production and differentiation of mature and functionally active neutrophils from bone marrow precursor cells. [2]
pain associated with osteoarthritis in dogs [36] Begelomab [6] mab: mouse: DPP4: Belantamab mafodotin [5] Blenrep: mab: humanized: B-cell maturation antigen (BCMA) Y (Withdrawn) relapsed or refractory multiple myeloma Belimumab [37] Benlysta: mab: human: B-cell activating factor (BAFF) Y: systemic lupus erythematosus without renal or CNS ...
Examples of periosteal reactive bone in selected specimens of Triceratops. A periosteal reaction can result from a large number of causes, including injury and chronic irritation due to a medical condition such as hypertrophic osteopathy, bone healing in response to fracture, chronic stress injuries, subperiosteal hematomas, osteomyelitis, and cancer of the bone.
Tumors cause pain by crushing or infiltrating tissue, triggering infection or inflammation, or releasing chemicals that make normally non-painful stimuli painful. Invasion of bone by cancer is the most common source of cancer pain.