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Side effects may include increased bowel gas, abdominal pain, and nausea. [3] Rare but serious side effects may include an abnormal heartbeat, seizures, and kidney problems. [8] Use appears to be safe during pregnancy. [9] [3] It is classified as an osmotic laxative: [4] It works by increasing the amount of water in the stool. [5]
[5] [6] This compound is a stimulant laxative and increases peristalsis in the gut. [5] [7] Sodium picosulfate is typically prescribed in a combined formulation with magnesium citrate, an osmotic laxative. This combination is a highly effective laxative, often prescribed to patients for bowel cleansing prior to colonoscopies. [5] [8]
Common side effects include abdominal bloating and cramps. [3] A potential exists for electrolyte problems as a result of the diarrhea it produces. [3] No evidence of harm to the fetus has been found when used during pregnancy. [3] It is generally regarded as safe during breastfeeding. [5] It is classified as an osmotic laxative. [6]
Stimulant laxatives, another type, stimulate the smooth muscle of the bowel to contract, but they often have more side effects, Chang notes. Use a laxative just on occasion when you need it.
Side effects are uncommon and typically mild, [1] and may include stomach pain, abdominal cramps or diarrhea, [1] Efficacy decreases with long-term use, and may cause poor bowel function. [9] Serious allergic reactions may occur with the drug. The most severe side effect of docusate, although very rare, is rectal bleeding. [23]
Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel. The increased water content softens the stool and stimulates the bowel to contract (move its ...
A study looked at the effects of calcium polycarbophil on general irritable bowel syndrome (IBS) symptoms. Fourteen patients with IBS-diarrhea and twelve with IBS-constipation were given calcium polycarbophil for eight weeks and their colon transit times were measured with radiopaque markers in the colon. The patients with diarrhea reported ...
Osmotic laxatives such as magnesium citrate work within minutes to eight hours for onset of action, and even then they may not be sufficient to expel the stool. [citation needed] Osmotic laxatives can cause cramping and even severe pain as the patient's attempts to evacuate the contents of the rectum are blocked by the fecal mass.
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