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Soman (or GD, EA 1210, Zoman, PFMP, A-255, systematic name: O-pinacolyl methylphosphonofluoridate) [1] is an extremely toxic chemical substance. It is a nerve agent , interfering with normal functioning of the mammalian nervous system by inhibiting the enzyme cholinesterase .
Of this, about 2.5 g is contained in the hemoglobin needed to carry oxygen through the blood (around 0.5 mg of iron per mL of blood), [8] and most of the rest (approximately 2 grams in adult men, and somewhat less in women of childbearing age) is contained in ferritin complexes that are present in all cells, but most common in bone marrow ...
The blood of people killed by blood agents is bright red, because the agents inhibit the use of the oxygen in it by the body's cells. [2] Cyanide poisoning can be detected by the presence of thiocyanate or cyanide in the blood, a smell of bitter almonds, or respiratory tract inflammations and congestions in the case of cyanogen chloride ...
Stereoisomers of Soman, a G-series nerve agent and suicide inhibitor of acetylcholinesterase.Note the non-carbon chiral center.. In biochemistry, suicide inhibition, also known as suicide inactivation or mechanism-based inhibition, is an irreversible form of enzyme inhibition that occurs when an enzyme binds a substrate analog and forms an irreversible complex with it through a covalent bond ...
A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).
Drug metabolism is the metabolic breakdown of drugs by living organisms, usually through specialized enzymatic systems. More generally, xenobiotic metabolism (from the Greek xenos "stranger" and biotic "related to living beings") is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as any drug ...
An Astrocyte, a cell notable for maintaining the blood brain barrier. Ammonia toxicity is often seen through two routes of administration, either through consumption or through endogenous ailments such as liver failure. [89] [90] One notable case in which ammonia toxicity is common is in response to cirrhosis of the liver which results in ...
Phoratoxin is hemolytic and causes cell leakage and cell lysis by interacting with the phospholipids. [8] This is used in a study for cancer treatment. The phoratoxin lyses the cancer cells, killing them. It supposedly helps with the chemotherapy and radiation as well, but little research has been done on this subject.