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The anticonvulsant drug, lamotrigine, has been associated with a decrease in white blood cell count. [ 2 ] The FDA monograph for metronidazole states that this medication can also cause leukopenia, and the prescriber information suggests a complete blood count, including differential cell count, before and after, in particular, high-dose therapy.
Methotrexate was originally developed and continues to be used for chemotherapy, either alone or in combination with other agents.It is effective for the treatment of several cancers, including solid tumours of breast, head and neck, lung, bladder, as well as acute lymphocytic leukemias, non-Hodgkin's lymphoma, osteosarcoma, and choriocarcinoma and other trophoblastic neoplasms.
Because the bone marrow is the manufacturing center of blood cells, the suppression of bone marrow activity causes a deficiency of blood cells. This condition can rapidly lead to life-threatening infection , as the body cannot produce leukocytes in response to invading bacteria and viruses , as well as leading to anaemia due to a lack of red ...
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Vertigo may be associated with rheumatoid arthritis via the following associations that can cause vertigo: Ménière's disease [45] [46] "Biologic disease-modifying antirheumatic drugs" [47] This may not happen in the absence of infection. [48] Atlanto-axial joint instability can cause symptoms including vertigo and sudden death. [49]
Methotrexate can also lead to pulmonary toxicity (lung damage), although this is fairly uncommon and more commonly it can confound the leukopenia caused by sarcoidosis. [19] Due to these safety concerns it is often recommended that methotrexate is combined with folic acid in order to prevent toxicity. [ 19 ]
Methotrexate treats cancer, lupus, rheumatoid arthritis, psoriasis but can cause birth defects. Some women can't get it because of abortion laws, fear punishment.
Thrombocytopenia can be contrasted with the conditions associated with an abnormally high level of platelets in the blood – thrombocythemia (when the cause is unknown), and thrombocytosis (when the cause is known).
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