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Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.
Linezolid is a member of the oxazolidinone class of medications. [10] Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. [16] [17] It is on the World Health Organization's List of Essential Medicines. [18] The World Health Organization classifies linezolid as critically important for human medicine. [19]
Linezolid (Zyvox), which is available for intravenous administration and also has the advantage of having excellent oral bioavailability. Posizolid , which appears to have excellent, targeted bactericidal activity against all common gram-positive bacteria, regardless of resistance to other classes of antibiotics.
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
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Skeletal formula of the antibiotic linezolid, highlighting the oxazolidinone pharmacophore (in blue) and desirable structural characteristics (in orange). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 24 June 2009: Source: Own work based on: Brickner SJ (1996).
4-Isoxazolidinone 5-Isoxazolidinone [1192-07-0] [2168656-08-2] [98026-51-8] 2-Oxazolidinone is the parent compound of several protein synthesis inhibitor antibiotics ...
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. [1] They are used in human and veterinary medicine to treat bacterial infections , as well as in animal husbandry , specifically poultry production .