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The limbic system, ... Its various components support a variety of functions including ... using electrodes to stimulate different parts of the brain in conscious ...
MFB is not the sole anatomical substrate responsible for reinforcing brain stimulation; however, it is the main tract for the ascending dopamine fibers, and it functions to relay information from the VTA to the nucleus accumbens. The rewarding effect of MFB stimulation is mediated via the activation of the mesocorticolimbic dopamine system. [1]
Chronic subcortical electrode implant in a laboratory rat used to deliver electrical stimulation to the brain. Electrical brain stimulation (EBS), also referred to as focal brain stimulation (FBS), is a form of electrotherapy and neurotherapy used as a technique in research and clinical neurobiology to stimulate a neuron or neural network in the brain through the direct or indirect excitation ...
Human brain in the coronal orientation. Amygdalae are shown in dark red. The amygdala (/ ə ˈ m ɪ ɡ d ə l ə /; pl.: amygdalae / ə ˈ m ɪ ɡ d ə l i,-l aɪ / or amygdalas; also corpus amygdaloideum; Latin from Greek, ἀμυγδαλή, amygdalē, 'almond', 'tonsil' [1]) is a paired nuclear complex present in the cerebral hemispheres of vertebrates.
An addictive drug is defined as a substance that affects the mesolimbic system directly or indirectly by increasing extracellular levels of dopamine. [ 24 ] Common addictive substances such as cocaine , alcohol , and nicotine have been shown to increase extracellular levels of dopamine within the mesolimbic pathway, preferentially within the ...
The mesocorticolimbic pathway originates through the VTA and passes through the amygdala, nucleus accumbens, and hippocampus. These functions are relative to memory, emotional regulation, motivation, and reward. The mesocorticolimbic system (mesocorticolimbic circuit) refers to both the mesocortical and mesolimbic pathways.
The reward system (the mesocorticolimbic circuit) is a group of neural structures responsible for incentive salience (i.e., "wanting"; desire or craving for a reward and motivation), associative learning (primarily positive reinforcement and classical conditioning), and positively-valenced emotions, particularly ones involving pleasure as a core component (e.g., joy, euphoria and ecstasy).
Since the limbic system consists of evolutionary primitive structures which prevents its interpretation verbally, the visceral brain accounts for the visual, auditory, olfactory, and other external sensory inputs that are associated with emotions. [20] Recently, many studies have been done to analyze the anatomy and function of the Papez circuit.