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For example, treatment of benzenediazonium chloride with benzene (an aromatic compound) in the presence of sodium hydroxide gives diphenyl: [C 6 H 5 N 2] + Cl − + C 6 H 6 → (C 6 H 5) 2 + N 2 + HCl. This reaction is known as the Gomberg–Bachmann reaction. A similar conversion is also achieved by treating benzenediazonium chloride with ...
In short-term toxicity studies in animals, the typical effects are anorexia and wasting, and even after a huge dose animals die only 1 to 6 weeks after the TCDD administration. [36] Seemingly similar species have varying sensitivities to acute effects: lethal dose for a guinea pig is about 1 μg/kg, but to a hamster it is more than 1,000 μg/kg.
Nitazoxanide alone has shown preliminary evidence of efficacy in the treatment of chronic hepatitis B over a one-year course of therapy. [17] Nitazoxanide 500 mg twice daily resulted in a decrease in serum HBV DNA in all of 4 HBeAg-positive patients, with undetectable HBV DNA in 2 of 4 patients, loss of HBeAg in 3 patients, and loss of HBsAg in one patient.
4-Nitrochlorobenzene is the organic compound with the formula ClC 6 H 4 NO 2. It is a pale yellow solid. It is a pale yellow solid. 4-Nitrochlorobenzene is a common intermediate in the production of a number of industrially useful compounds, including antioxidants commonly found in rubber .
Hemangiosarcoma is a rapidly growing, highly invasive variety of cancer that occurs almost exclusively in dogs, and only rarely in cats, horses, mice, [1] or humans (vinyl chloride toxicity). It is a sarcoma arising from the lining of blood vessels; that is, blood-filled channels and spaces are commonly observed microscopically. A frequent ...
Afoxolaner (INN [5]) is an insecticide and acaricide that belongs to the isoxazoline chemical compound group.. It acts as an antagonist at GABA-receptors (those gated by the neurotransmitter gamma-aminobutyric acid) and other ligand-gated chloride channels.
2,4-Dinitrochlorobenzene (DNCB) is an organic compound with the chemical formula (O 2 N) 2 C 6 H 3 Cl. It is a yellow solid that is soluble in organic solvents . It is an intermediate for the industrial production of other compounds.
The toxic effects were attributed to HCl formation, as benzotrichloride dissociates rapidly into the far less toxic benzoic acid and HCl on water exposure. Compensating the pH decrease in water from the HCl negated toxic effects, suggesting that water acidification is the reason for the low aquatic life toxicity. [ 20 ]
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