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Annonacin is a disabling and potentially lethal neurotoxin. [4] [5] [6] Like other acetogenins, it is a mitochondrial complex I (NADH-dehydrogenase) inhibitor. [5]As NADH-dehydrogenase is responsible for the conversion of NADH to NAD+ as well as the establishment of a proton gradient in the mitochondria, annonacin disables the ability of a cell to generate ATP through oxidative phosphorylation ...
A. muricata flower. Soursop (also called graviola, guyabano, and in Latin America guanábana) is the fruit of Annona muricata, a broadleaf, flowering, evergreen tree. [4] [5] It is native to the tropical regions of the Americas and the Caribbean and is widely propagated. [5] It is in the same genus, Annona, as cherimoya and is in the Annonaceae ...
The acetogenin compounds, which occur in the fruit, seeds, and leaves of many Annonaceae, including soursop (Annona muricata), are neurotoxins and seem to be the cause of a neurodegenerative disease. The disorder is a so-called tauopathy associated with a pathologic accumulation of tau protein in the brain. Experimental results indicate that ...
A daily fiber supplement may improve brain function, new research finds. In just 12 weeks, researchers found that those who received a daily fiber supplement were performing better in tests ...
Annonamine is a benzylisoquinoline alkaloid isolated from Annona muricata [1] (commonly known as soursop, graviola, guanabana, paw-paw and sirsak), a plant commonly used in folk medicine by indigenous communities in Africa and South America. [2] Structurally, it contains an aporphine core featuring a quaternary ammonium group.
Annona or Anona (from Taíno annon) is a genus of flowering plants in the pawpaw/sugar apple family, Annonaceae. It is the second largest genus in the family after Guatteria , [ 3 ] containing approximately 166 [ 4 ] species of mostly Neotropical and Afrotropical trees and shrubs .
Annona montana, the mountain soursop, is a tree and its edible fruit in the Annonaceae family native to Central America, the Amazon, and islands in the Caribbean. It has fibrous fruits. [ 4 ] A. montana may be used as a rootstock for cultivated Annonas .
The cherimoya (Annona cherimola), also spelled chirimoya and called chirimuya by the Quechua people, is a species of edible fruit-bearing plant in the genus Annona, from the family Annonaceae, which includes the closely related sweetsop and soursop.