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Gestational diabetes is a form of diabetes that is first diagnosed during pregnancy and can accordingly cause high blood sugar that affects the woman and the baby. [9] In 10 - 20% of women whose diet and exercise are not adequate enough to control blood sugar, insulin injections may be required to lower blood sugar levels. [9]
[105] [106] However, another study found that pregabalin and gabapentin had similar affinities for the human recombinant α 2 δ-1 subunit (K i =32 nM and 40 nM, respectively). [107] In any case, pregabalin is 2 to 4 times more potent than gabapentin as an analgesic [ 102 ] [ 108 ] and, in animals, appears to be 3 to 10 times more potent than ...
There are pre- and post-natal exposure risk of neurobehavioral disorders. The exposure during pregnancy can alter the newborn infants' short and long term adverse effects. This can include low birth weight, reduced head circumference, cognitive deficits, emotional dysregulation, high impulsiveness, and higher risk to develop a substance ...
Alcohol: Use during pregnancy can cause fetal alcohol syndrome and fetal alcohol spectrum disorder. [67] Tobacco use: During pregnancy, causes twice the risk of premature rupture of membranes, placental abruption and placenta previa. [68] Also, it increases the odds of the baby being born prematurely by 30%. [69]
According to a study conducted by Whitcome, et al., lumbar lordosis can increase from an angle of 32 degrees at 0% fetal mass (i.e. non-pregnant women or very early in pregnancy) to 50 degrees at 100% fetal mass (very late in pregnancy). Postpartum, the angle of the lordosis declines and can reach the angle prior to pregnancy.
The new study found that women who had higher levels of fluoride during pregnancy reported later that their kids were more likely to have temper tantrums, complain of vague headaches and ...
A Phase 0 study gives no data on safety or efficacy, being by definition a dose too low to cause any therapeutic effect. Drug development companies carry out Phase 0 studies to rank drug candidates to decide which has the best pharmacokinetic parameters in humans to take forward into further development. They enable go/no-go decisions to be ...
The course of asthma during pregnancy can vary, with some patients experiencing worsening symptoms while others see improvement. As of 2006, it was believed the course of asthma during pregnancy varied with a similar proportion of women improving, remaining stable, or worsening. [ 35 ]