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Carotid IMT is used to detect the presence of atherosclerosis in humans and, more contentiously, to track the regression, arrest or progression of atherosclerosis. [1] Ultrasound measurements of carotid IMT were first proposed and validated in vitro by Paolo Pignoli in 1984 [2] and further details were subsequently published in a highly cited ...
Common symptoms of IMT include lethargy, anorexia, pyrexia, haemorrhage, and bruising. [1] Destruction of platelets occurs when immunoglobins attach to the surface of the platelet, which causes macrophages to initiate phagocytosis. [2] IMT is differentiated from other forms of thrombocytopaenia by the immune-mediated component of the condition. [3]
The Simplified Acute Physiology Score III (SAPS III) is a system for predicting mortality, one of several ICU scoring systems. It is a supplement to the SAPS II scoring system. It has been designed to provide a real-life predicted mortality for a patient by following a well defined procedure, based on a mathematical model that needs calibration .
SAPS II was designed to measure the severity of disease for patients admitted to Intensive care units aged 18 or more.. 24 hours after admission to the ICU, the measurement has been completed and resulted in an integer point score between 0 and 163 and a predicted mortality between 0% and 100%.
APACHE II ("Acute Physiology and Chronic Health Evaluation II") is a severity-of-disease classification system, [1] one of several ICU scoring systems.It is applied within 24 hours of admission of a patient to an intensive care unit (ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.
Also known as 'effort angina', this refers to the classic type of angina related to myocardial ischemia.A typical presentation of stable angina is that of chest discomfort and associated symptoms precipitated by some activity (running, walking, etc.) with minimal or non-existent symptoms at rest or after administration of sublingual nitroglycerin. [11]
Micrograph showing an ALK positive adenocarcinoma of the lung.The ALK immunostain allows individuals with ALK rearrangements to be identified.. ALK inhibitors are anti-cancer drugs that act on tumours with variations of anaplastic lymphoma kinase (ALK) such as an EML4-ALK translocation. [1]
It should increase within 2–3 days of a major acute hemorrhage, for instance, and reach its peak in 6–10 days. [3] If reticulocyte production is not raised in response to anemia, then the anemia may be due to an acute cause with insufficient time to compensate, or there is a defect with red blood cell production in the bone marrow.