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  2. Ribosomopathy - Wikipedia

    en.wikipedia.org/wiki/Ribosomopathy

    These are transcribed in the nucleolus by RNA polymerase I. 45S is processed in the nucleus via 32S rRNA to 28S [6] and 5.8S, [7] and via 30S to 18S, [8] as shown in the diagram. 18S is a component of the ribosomal 40S subunit. 28S, 5.8S and 5S, [9] which is transcribed independently, are components

  3. Category:Nucleus diseases - Wikipedia

    en.wikipedia.org/wiki/Category:Nucleus_diseases

    Pages in category "Nucleus diseases" The following 6 pages are in this category, out of 6 total. This list may not reflect recent changes. C. Cornelia de Lange ...

  4. Nucleolus - Wikipedia

    en.wikipedia.org/wiki/Nucleolus

    The nucleolus (/ nj uː ˈ k l iː ə l ə s, ˌ nj uː k l i ˈ oʊ l ə s /; pl.: nucleoli /-l aɪ /) is the largest structure in the nucleus of eukaryotic cells. [1] It is best known as the site of ribosome biogenesis. The nucleolus also participates in the formation of signal recognition particles and plays a role in the cell's response to ...

  5. DNA repair-deficiency disorder - Wikipedia

    en.wikipedia.org/wiki/DNA_repair-deficiency_disorder

    DNA repair defects are seen in nearly all of the diseases described as accelerated aging disease, in which various tissues, organs or systems of the human body age prematurely. Because the accelerated aging diseases display different aspects of aging, but never every aspect, they are often called segmental progerias by biogerontologists .

  6. Cell nucleus - Wikipedia

    en.wikipedia.org/wiki/Cell_nucleus

    Diagram of the nucleus showing the ribosome-studded outer nuclear membrane, nuclear pores, DNA (complexed as chromatin), and the nucleolus. The nucleus contains nearly all of the cell's DNA, surrounded by a network of fibrous intermediate filaments called the nuclear matrix, and is enveloped in a double membrane called the nuclear envelope.

  7. Basal ganglia disease - Wikipedia

    en.wikipedia.org/wiki/Basal_ganglia_disease

    It is generally caused by damage to the subthalamic nucleus (STN). Since the internal segment of the globus pallidus (GPi) is the link in the circuit between the STN and thalamic projection, destruction of localized brain cells in the GPi via a pallidotomy has proven to serve as a useful treatment for hemiballismus.

  8. Giant cell - Wikipedia

    en.wikipedia.org/wiki/Giant_cell

    Giant cell arteritis, [6] also known as temporal arteritis or cranial arteritis, is the most common MGC-linked disease. This type of arteritis causes the arteries in the head, neck, and arm area to swell to abnormal sizes. Although the cause of this disease is not currently known, it appears to be related to polymyalgia rheumatica. [7]

  9. Proteinopathy - Wikipedia

    en.wikipedia.org/wiki/Proteinopathy

    In medicine, proteinopathy ([pref. protein]; -pathy [suff. disease]; proteinopathies pl.; proteinopathic adj), or proteopathy, protein conformational disorder, or protein misfolding disease, is a class of diseases in which certain proteins become structurally abnormal, and thereby disrupt the function of cells, tissues and organs of the body.