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  2. Nucleolus - Wikipedia

    en.wikipedia.org/wiki/Nucleolus

    The nucleolus (/ nj uː ˈ k l iː ə l ə s, ˌ nj uː k l i ˈ oʊ l ə s /; pl.: nucleoli /-l aɪ /) is the largest structure in the nucleus of eukaryotic cells. [1] It is best known as the site of ribosome biogenesis. The nucleolus also participates in the formation of signal recognition particles and plays a role in the cell's response to ...

  3. Ribosomopathy - Wikipedia

    en.wikipedia.org/wiki/Ribosomopathy

    These are transcribed in the nucleolus by RNA polymerase I. 45S is processed in the nucleus via 32S rRNA to 28S [6] and 5.8S, [7] and via 30S to 18S, [8] as shown in the diagram. 18S is a component of the ribosomal 40S subunit. 28S, 5.8S and 5S, [9] which is transcribed independently, are components

  4. Cajal body - Wikipedia

    en.wikipedia.org/wiki/Cajal_body

    Cajal bodies (CBs), also coiled bodies, are spherical nuclear bodies of 0.3–1.0 μm in diameter found in the nucleus of proliferative cells like embryonic cells and tumor cells, or metabolically active cells like neurons. CBs are membrane-less organelles and largely consist of proteins and RNA.

  5. Nuclear bodies - Wikipedia

    en.wikipedia.org/wiki/Nuclear_bodies

    Nuclear bodies were first seen as prominent interchromatin structures in the nuclei of malignant or hyperstimulated animal cells [7] [8] identified using anti-sp100 autoantibodies from primary biliary cirrhosis and subsequently the promyelocytic leukemia (PML) factor, but appear also to be elevated in many autoimmune and cancerous diseases. [9]

  6. Category:Nucleus diseases - Wikipedia

    en.wikipedia.org/wiki/Category:Nucleus_diseases

    Pages in category "Nucleus diseases" The following 6 pages are in this category, out of 6 total. This list may not reflect recent changes. C. Cornelia de Lange ...

  7. Cell nucleus - Wikipedia

    en.wikipedia.org/wiki/Cell_nucleus

    Diagram of the nucleus showing the ribosome-studded outer nuclear membrane, nuclear pores, DNA (complexed as chromatin), and the nucleolus. The nucleus contains nearly all of the cell's DNA, surrounded by a network of fibrous intermediate filaments called the nuclear matrix, and is enveloped in a double membrane called the nuclear envelope.

  8. Chromatolysis - Wikipedia

    en.wikipedia.org/wiki/Chromatolysis

    The event of chromatolysis is also characterized by a prominent migration of the nucleus towards the periphery of the cell and an increase in the size of the nucleolus, nucleus, and cell body. [1] The term "chromatolysis" was initially used in the 1940s to describe the observed form of cell death characterized by the gradual disintegration of ...

  9. Micronucleus - Wikipedia

    en.wikipedia.org/wiki/Micronucleus

    Micronuclei are commonly seen in cancerous cells and may indicate genomic damage events that can increase the risk of developmental or degenerative diseases. [ 1 ] Micronuclei form during anaphase from lagging acentric chromosomes or chromatid fragments caused by incorrectly repaired or unrepaired DNA breaks or by nondisjunction of chromosomes.