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Phenylglycine is the organic compound with the formula C 6 H 5 CH(NH 2)CO 2 H. It is a non-proteinogenic alpha amino acid related to alanine, but with a phenyl group in place of the methyl group. It is a white solid. The compound exhibits some biological activity. [1]
N-Phenylglycine is an organic compound with the formula C 6 H 5 NHCH 2 CO 2 H. This white solid achieved fame as the industrial precursor to indigo dye. [1] It is a non-proteinogenic alpha amino acid related to sarcosine, but with an N-phenyl group in place of N-methyl.
[1] [2] Azlactone chemistry: step 2 is a Perkin variation. Hippuric acid, the benzamide derivative of glycine, cyclizes in the presence of acetic anhydride, condensing to give 2-phenyl-oxazolone. [3] This intermediate also has two acidic protons and reacts with benzaldehyde, acetic anhydride and sodium acetate to a so-called azlactone.
[1] (S)-DHPG has been investigated for therapeutic effects in the treatment of neuronal injury (such as those associated with ischemia or hypoxia), cognitive enhancement, and Alzheimer's disease. [1] 3,5-Dihydroxyphenylglycine can be isolated from the latex of Euphorbia helioscopia. [2] DHGP is also found in vancomycin and related glycopeptides.
Biosynthesis of HPG. HPG is synthesized from prephenate, an intermediate in the shikimic acid pathway and also a precursor to tyrosine.Prephenate is aromatized by prephenate dehydrogenase (Pdh) using NAD + as a cofactor to produce 4-hydroxyphenylpyruvate. 4-Hydroxyphenylpyruvate is then oxidized by 4-hydroxymandelate synthase (4HmaS) using oxygen to form 4-hydroxymandelate and hydrogen ...
A thesaurus (pl.: thesauri or thesauruses), sometimes called a synonym dictionary or dictionary of synonyms, is a reference work which arranges words by their meanings (or in simpler terms, a book where one can find different words with similar meanings to other words), [1] [2] sometimes as a hierarchy of broader and narrower terms, sometimes simply as lists of synonyms and antonyms.
It classifies substances as chemical, protein, nucleic acid, polymer, structurally diverse, or mixture [1] [2] according to the standards outlined by the International Organization for Standardization in ISO 11238 [3] and ISO DTS 19844. [4] UNIIs are non-proprietary, unique, unambiguous, and free to generate and use. [2]
Substituted phenylmorpholines, or substituted phenmetrazines alternatively, are chemical derivatives of 2-phenylmorpholine or of the psychostimulant drug phenmetrazine.Most such compounds act as releasers of monoamine neurotransmitters, and have stimulant effects.